BDBM251577 US9452998, 1

SMILES NC1CCN(CC1)c1cccnc1NC(=O)c1nc(cnc1N)-c1ncccc1C(F)(F)F

InChI Key InChIKey=KYJCVYZGCYEQEA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 251577   

TargetProtein kinase C alpha type(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 251577BDBM251577(US9452998, 1)
Affinity DataIC50: 2nMAssay Description:Inhibition of PKCalpha (unknown origin) incubated for 15 mins in presence of 33P-ATP by Topcount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein kinase C theta type(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 251577BDBM251577(US9452998, 1)
Affinity DataIC50: 5nMAssay Description:Inhibition of PKCtheta (unknown origin) incubated for 15 mins in presence of 33P-ATP by Topcount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed