BDBM251895 BDBM376543::US9475809, 7

SMILES O=C(Cn1c2c(c(-c3cc(Cl)ccc3Cl)cc1=O)C(=O)CC2)Nc1ccc(-c2cc(=O)[nH][nH]2)cc1

InChI Key InChIKey=AWILRXROPDAJAV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 251895   

TargetCoagulation factor XI(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 251895BDBM251895(US9475809, 7 | BDBM376543)
Affinity DataIC50: 130nMAssay Description:The factor XIa inhibition of the inventive substances is determined using a biochemical test system which utilizes the reaction of a peptidic factor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 251895BDBM251895(US9475809, 7 | BDBM376543)
Affinity DataIC50: 130nMpH: 7.4 T: 2°CAssay Description:The factor XIa inhibition of the inventive substances is determined using a biochemical test system which utilizes the reaction of a peptidic factor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent