BDBM25289 bisphosphonate, 38::{1-hydroxy-2-[3-(3-phenylphenyl)phenoxy]-1-phosphonoethyl}phosphonic acid
SMILES OC(COc1cccc(c1)-c1cccc(c1)-c1ccccc1)(P(O)(O)=O)P(O)(O)=O
InChI Key InChIKey=NWIARQRYIRVYCM-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 25289
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute Of Biological Chemistry
Curated by ChEMBL
Institute Of Biological Chemistry
Curated by ChEMBL
Affinity DataKi: 60nMAssay Description:Binding affinity to Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute Of Biological Chemistry
Curated by ChEMBL
Institute Of Biological Chemistry
Curated by ChEMBL
Affinity DataKi: 110nMAssay Description:Binding affinity to human GGPPSMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute Of Biological Chemistry
Curated by ChEMBL
Institute Of Biological Chemistry
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute Of Biological Chemistry
Curated by ChEMBL
Institute Of Biological Chemistry
Curated by ChEMBL
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of human GGPPSMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute Of Biological Chemistry
Curated by ChEMBL
Institute Of Biological Chemistry
Curated by ChEMBL
Affinity DataIC50: 4.07E+3nMAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair