BDBM254570 US10214477, Example 29::US9469597, 29::US9670136, 29 N1-(2-(4-methoxyphenyl)cyclopropyl)cyclohexane-1,4-diamine
SMILES COc1ccc(cc1)C1CC1NC1CCC(N)CC1
InChI Key InChIKey=RETHRNCONJQITP-UHFFFAOYSA-N
Data 9 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 254570
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 37°CAssay Description:In order to monitor MAO enzymatic activities and/or their inhibition rate by inhibitor(s) of interest, a fluorescence-based (inhibitor)-screening ass...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 37°CAssay Description:In order to monitor MAO enzymatic activities and/or their inhibition rate by inhibitor(s) of interest, a fluorescence-based (inhibitor)-screening ass...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Lysine-specific histone demethylase 1A [158-852](Human)
Oryzon Genomics
US Patent
Oryzon Genomics
US Patent
Affinity DataIC50: 36nMpH: 7.4 T: 37°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Briefly, a fixed amount of MAO (0.25 μg for MAO-A and 0.5 μg for MAO-B) was incubated on ice for 15 minutes in the reaction buffer, in the ...More data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...More data for this Ligand-Target Pair
Affinity DataIC50: 36nMpH: 7.4 T: 25°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Briefly, a fixed amount of MAO (0.25 μg for MAO-A and 0.5 μg for MAO-B) was incubated on ice for 15 minutes in the reaction buffer, in the ...More data for this Ligand-Target Pair