BDBM254845 US9493412, 8

SMILES CN1CC(C(=O)NCc2ccc(Oc3ccc(F)cc3)cc2)=C(O)C1=O

InChI Key InChIKey=WQDGXNQDSQPULS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 254845   

TargetEndothelial lipase(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM254845(US9493412, 8)
Affinity DataIC50: 49.5nMpH: 8.0Assay Description:Endothelial lipase activity was measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artificial vesicle containing DMPG (Av...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
US Patent