BDBM254864 US9493412, 157

SMILES CN1CC(C(=O)NCC2CCN(CC2)C(=O)c2ccc(Cl)c(Cl)c2)=C(O)C1=O

InChI Key InChIKey=XHFYDOOANISKRL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 254864   

TargetEndothelial lipase(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM254864(US9493412, 157)
Affinity DataIC50: 4.84E+3nMpH: 8.0Assay Description:Endothelial lipase activity was measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artificial vesicle containing DMPG (Av...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
US Patent