BDBM25499 4-(4-chloro-2-fluorophenyl)-2-(2-ethoxypyridin-4-yl)-N-(6-fluoro-1H-indazol-5-yl)-6-methyl-1,4-dihydropyrimidine-5-carboxamide::Dihydropyrimidine, 28

SMILES CCOc1cc(C2=NC(C)=C(C(=O)Nc3cc4cn[nH]c4cc3F)C(c3ccc(Cl)cc3F)N2)ccn1

InChI Key InChIKey=DSPVWAIHVFERDQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25499   

LigandChemical structure of BindingDB Monomer ID 25499BDBM25499(4-(4-chloro-2-fluorophenyl)-2-(2-ethoxypyridin-4-y...)
Affinity DataIC50: 11nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP33, and the incorporation of P33 into the peptide was quantified by Sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed