BDBM2550 5-tert-butyl-4-({6-cyclohexyl-4-hydroxy-6-[2-(4-hydroxyphenyl)ethyl]-2-oxo-5,6-dihydro-2H-pyran-3-yl}sulfanyl)-2-methylphenyl N,N-dimethylsulfamate::6-Alkyl-5,6-Dihydropyran-2-one 26

SMILES CN(C)S(=O)(=O)Oc1cc(c(SC2C(=O)CC(CCc3ccc(O)cc3)(OC2=O)C2CCCCC2)cc1C)C(C)(C)C

InChI Key InChIKey=DILLCIICWVEDNF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2550   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM2550(5-tert-butyl-4-({6-cyclohexyl-4-hydroxy-6-[2-(4-hy...)
Affinity DataIC50: 20nMpH: 6.2 T: 2°CAssay Description:For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2004
Entry Details Article
PubMed