BDBM25535 2-(hydroxymethyl)-7,8-dimethoxy-5-methylphenanthridin-5-ium chloride::chelerythrine analogue, 33

SMILES COc1ccc2c(c[n+](C)c3ccc(CO)cc23)c1OC

InChI Key InChIKey=QBHJTSNVUACDMT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25535   

TargetBcl-2-like protein 1(Human)
A* Star

LigandPNGBDBM25535(2-(hydroxymethyl)-7,8-dimethoxy-5-methylphenanthri...)
Affinity DataIC50: 1.00E+5nMpH: 8.0 T: 2°CAssay Description:In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex...More data for this Ligand-Target Pair
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Date in BDB:
11/22/2008
Entry Details Article
PubMed