BDBM255356 US9481682, 106

SMILES Nc1nccn2c(nc(-c3ccc(cc3)C(=O)Nc3cc4ccccc4cn3)c12)[C@@H]1CC[C@H]2CCC(=O)N2C1

InChI Key InChIKey=PSCLFLZFONSYNH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 255356   

TargetTyrosine-protein kinase BTK(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM255356(US9481682, 106)
Affinity DataIC50: 0.190nMAssay Description:BTK enzymatic activity was determined with the LANCE (Lanthanide Chelate Excite) TR-FRET (Time-resolved fluorescence resonance energy transfer) assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
US Patent