BDBM25748 3-(2-{[3-(2-cyanophenoxy)-2-hydroxypropyl]amino}ethyl)-1-phenylurea::ICI 89,406::ICI 89406
SMILES OC(CNCCNC(=O)Nc1ccccc1)COc1ccccc1C#N
InChI Key InChIKey=HTLWRKRZKFAAAH-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 25748
Affinity DataKd: 85nMAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
Affinity DataKd: 2.04E+3nMAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
Affinity DataKd: 0.331nMAssay Description:Antagonist activity at human beta1 adrenoceptor expressed in CHOK1 cells assessed as inhibition of cimaterol-induced [3H]cAMP accumulation incubated ...More data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+4nMAssay Description:Agonist activity at human beta3 adrenoceptor expressed in CHOK1 cells assessed as induction of [3H]cAMP accumulation after 5 hrsMore data for this Ligand-Target Pair
Affinity DataKd: 56nMAssay Description:Antagonist activity at human beta2 adrenoceptor expressed in CHOK1 cells assessed as inhibition of cimaterol-induced [3H]cAMP accumulation incubated ...More data for this Ligand-Target Pair
Affinity DataKd: 1.80nMAssay Description:Displacement of [3H]-CGP12177 from human beta1 adrenoceptor expressed in CHOK1 cells after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKd: 1.91E+3nMAssay Description:Antagonist activity at human beta3 adrenoceptor expressed in CHOK1 cells assessed as inhibition of cimaterol-induced [3H]cAMP accumulation incubated ...More data for this Ligand-Target Pair
Affinity DataEC50: 60nMAssay Description:Agonist activity at human beta2 adrenoceptor expressed in CHOK1 cells assessed as induction of [3H]cAMP accumulation after 5 hrsMore data for this Ligand-Target Pair
Affinity DataKd: 145nMAssay Description:Displacement of [3H]-CGP12177 from human beta2 adrenoceptor expressed in CHOK1 cells after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKd: 1.24nMpH: 7.4 T: 37°CAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
Affinity DataEC50: 0.813nMAssay Description:Partial agonist activity at human beta1 adrenoceptor expressed in CHOK1 cells assessed as induction of [3H]cAMP accumulation after 5 hrsMore data for this Ligand-Target Pair