BDBM257502 US9505736, (1R,2S,3S)-2-(8-Chloro-2,3- dihydrobenzo[b][1,4]dioxin-6-yl)-1- fluoro-N-hydroxy-3- phenylcyclopropanecarboxamide

SMILES ONC(=O)[C@@]1(F)[C@@H]([C@H]1c1cc(Cl)c2OCCOc2c1)c1ccccc1

InChI Key InChIKey=TZNSBMGNVJVYIP-IIDMSEBBSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 257502   

TargetHistone deacetylase 4 [648-729,745-1057](Human)
Chdi Foundation

US Patent
LigandPNGBDBM257502(US9505736, (1R,2S,3S)-2-(8-Chloro-2,3- dihydrobenz...)
Affinity DataIC50:  6.47E+3nMpH: 8.0 T: 25°CAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent