BDBM257503 US9505736, (1S,2S,3S)-1-Fluoro-N-hydroxy-2-(4-(5- methylpyrimidin-2-yl)phenyl)-3- phenylcyclopropanecarboxamide

SMILES Cc1cnc(nc1)-c1ccc(cc1)[C@@H]1[C@@H](c2ccccc2)[C@@]1(F)C(=O)NO

InChI Key InChIKey=LERFWXLGVNOQCJ-OPYAIIAOSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 257503   

TargetHistone deacetylase 4 [648-729,745-1057](Human)
Chdi Foundation

US Patent
LigandPNGBDBM257503(US9505736, (1S,2S,3S)-1-Fluoro-N-hydroxy-2-(4-(5- ...)
Affinity DataIC50:  20nMpH: 8.0 T: 25°CAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent