BDBM257509 US9505736, (1S,2R,3S)-1-Fluoro-2-(2-(4- fluorophenyl)thiazol-5-yl)-N-hydroxy-3- phenylcyclopropanecarboxamide

SMILES ONC(=O)[C@@]1(F)[C@@H]([C@H]1c1ccccc1)c1cnc(s1)-c1ccc(F)cc1

InChI Key InChIKey=QZEPBMKPUBUIIG-MDZRGWNJSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 257509   

TargetHistone deacetylase 4 [648-729,745-1057](Human)
Chdi Foundation

US Patent
LigandPNGBDBM257509(US9505736, (1S,2R,3S)-1-Fluoro-2-(2-(4- fluorophen...)
Affinity DataIC50:  60nMpH: 8.0 T: 25°CAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent