BDBM258593 US9493490, 6-(4-(aminomethyl)-2-chlorophenoxy)-7-chlorobenzo[c][1,2]oxaborol-1(3H)-ol::US9493490, B::US9493490, Example 2
SMILES NCc1ccc(Oc2ccc3COB(O)c3c2Cl)c(Cl)c1
InChI Key InChIKey=VGXUHSXKJLKRBG-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 258593
TargetGlutathione S-transferase P/Rho-associated protein kinase 1 [1-535](Homo sapiens (Human))
Anacor Pharmaceuticals
US Patent
Anacor Pharmaceuticals
US Patent
Affinity DataIC50: 2.30E+4nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Rho-associated protein kinase 2 [5-554](Homo sapiens (Human))
Anacor Pharmaceuticals
US Patent
Anacor Pharmaceuticals
US Patent
Affinity DataIC50: 1.60E+4nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Rho-associated protein kinase 1 [1-535](Homo sapiens (Human))
Anacor Pharmaceuticals
US Patent
Anacor Pharmaceuticals
US Patent
Affinity DataIC50: 1.10E+4nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair