BDBM258747 US9499482, 146

SMILES COc1cc(ccc1OCCN1CC[C@@H](F)C1)N1CC=C(Oc2ccc(cc2)C2CC2)C1=O

InChI Key InChIKey=MHMJMMVEKXJVCO-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 258747   

TargetMelanin-concentrating hormone receptor 1 [E4Q,A5T](Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM258747(US9499482, 146)
Affinity DataKi:  0.600nMpH: 7.4Assay Description:An in vitro binding assay was used to determine the compound Ki value or ability to antagonize binding of a peptide agonist to the human melanin conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

LigandPNGBDBM258747(US9499482, 146)
Affinity DataKi:  0.620nMAssay Description:Displacement of [125I]MCH from rat MCHR1 extracted from HEK293 cell membrane assessed as inhibition constant by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM258747(US9499482, 146)
Affinity DataKi:  0.640nMAssay Description:Displacement of [125I]MCH from human MCHR1 extracted from HEK293 cell membrane assessed as inhibition constant by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed