BDBM259375 US9505745, 52::US9790212, Example 52
SMILES CCN(CC)c1sc(Br)c(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C
InChI Key InChIKey=FOOXUZRFPGZBNI-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 259375
TargetHistone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED/Polycomb protein SUZ12/Zinc finger protein AEBP2(Homo sapiens (Human))
Glaxosmithkline
US Patent
Glaxosmithkline
US Patent
Affinity DataIC50: 316nMAssay Description:Compounds contained herein were evaluated for their ability to inhibit the methyltransferase activity of EZH2 within the PRC2 complex. Human PRC2 com...More data for this Ligand-Target Pair
TargetHistone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED/Polycomb protein SUZ12/Zinc finger protein AEBP2(Homo sapiens (Human))
Glaxosmithkline
US Patent
Glaxosmithkline
US Patent
Affinity DataIC50: 316nMAssay Description:Protocol 2: Compounds contained herein were evaluated for their ability to inhibit the methyltransferase activity of EZH2 within the PRC2 complex. Hu...More data for this Ligand-Target Pair