BDBM259390 US9505745, 67::US9790212, Example 67

SMILES CCN(C1CCNCC1F)c1scc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 259390   

LigandPNGBDBM259390(US9505745, 67 | US9790212, Example 67)
Affinity DataIC50:  20nMAssay Description:Compounds contained herein were evaluated for their ability to inhibit the methyltransferase activity of EZH2 within the PRC2 complex. Human PRC2 com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM259390(US9505745, 67 | US9790212, Example 67)
Affinity DataIC50:  20nMAssay Description:Protocol 2: Compounds contained herein were evaluated for their ability to inhibit the methyltransferase activity of EZH2 within the PRC2 complex. Hu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent