BDBM259876 US9505766, 81
SMILES COc1cc(cc(OC)c1OC)-c1n[nH]c2ccc(\C=C(/C#N)C(=O)NC(C)(C)CO)cc12
InChI Key InChIKey=FCCMYBKAZCDQGX-LZYBPNLTSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 259876 Sort by
TargetRibosomal protein S6 kinase alpha-3 [399-740](Human)
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataIC50: 3nMpH: 8.0 T: 22°CAssay Description:RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...More data for this Ligand-Target Pair
Affinity DataIC50: 0.631nMAssay Description:Inhibition of N-terminal His-Smt-tagged MSK1 C-terminal kinase domain (414 to 738 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of full-length N-terminal His-TEV-tagged inactive form of MSK1 (2 to 802 residues) (unknown origin) expressed in HEK293 cells using FAM-PS...More data for this Ligand-Target Pair