BDBM260349 US12630511, Example 1

SMILES O=C(N[C@@H](c1cc2ccccc2[nH]1)c1cc(F)ccc1O)c1cccc(-c2ccc(N3CCNCC3)cc2)c1

InChI Key InChIKey=PTVXHYVRUZTADK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 260349   

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 260349BDBM260349(US12630511, Example 1)
Affinity DataIC50: 46nMAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent