BDBM260471 US10428074, Example 36::US9527851, 36

SMILES COC(=O)N1CC[C@H]2CC(N(C)c3ncnc4[nH]ccc34)C[C@H]2C1

InChI Key InChIKey=QCBFFVVAONXLHM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 260471   

TargetTyrosine-protein kinase JAK1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 260471BDBM260471(US9527851, 36 | US10428074, Example 36)
Affinity DataIC50: 25nMAssay Description:JAK1: In vitro kinase assays described below can be used to determine the activity of a test compound for inhibiting the activity of JAK1 kinase. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 260471BDBM260471(US9527851, 36 | US10428074, Example 36)
Affinity DataIC50: 75nMAssay Description:JAK2: In vitro kinase assays described below can be used to determine the activity of a test compound for inhibiting the activity of JAK2 kinase. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent