BDBM260483 US12629358, Compound C3

SMILES CO[C@]1(C(=O)N[C@@H](C)c2ccc(-n3cc(F)cn3)nc2)CC[C@@H](c2nc(Nc3cc(C)[nH]n3)cc3cccnc32)CC1

InChI Key InChIKey=OQMXWPAKFUHRJX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 260483   

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Tyk Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 260483BDBM260483(US12629358, Compound C3)
Affinity DataIC50: 241nMAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2018
Entry Details
US Patent