BDBM2605 (Arylindolyl)maleimide deriv. 27::3-(1-methyl-1H-indol-3-yl)-4-{1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl}-2,5-dihydro-1H-pyrrole-2,5-dione
SMILES Cn1cc(C2=C(C(=O)NC2=O)c2cn(C)c3ncccc23)c2ccccc12
InChI Key InChIKey=XGISVNPAZQTTIQ-UHFFFAOYSA-N
Data 10 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 2605
Affinity DataIC50: 2.90E+3nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Rat)
University College Cork
Curated by ChEMBL
University College Cork
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant rat DYRK1A kinase domain expressed in bacteria using KKISGRLSPIMTEQ as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human haspin kinase domain expressed in bacteria using histone H3 (1 to 21 residues) peptide as substrate in presence of [g...More data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of recombinant full length human CDK5/p25 expressed in bacteria using histone H1 as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of recombinant full length human PIM1 expressed in bacteria using histone H1 as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 3(Human)
University College Cork
Curated by ChEMBL
University College Cork
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant full length human RIPK3 expressed in baculovirus infected Sf9 insect cells using MBP as substrate in presence of [gamma-33P...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta/[Tau protein] kinase(Pig)
University College Cork
Curated by ChEMBL
University College Cork
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of domestic porcine brain full length GSK-3alpha/beta using GS-1 as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant full length human aurora B expressed in baculovirus infected Sf9 insect cells using MBP as substrate in presence of [gamma-...More data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of recombinant full length human CDK9/cyclin T expressed in baculovirus infected Sf9 insect cells using YSPTSPSYSPTSPSYSPTSPSKKKK as subst...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of full length human CDK2/cyclin A using histone H1 as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair