BDBM26073 2-benzyl-3-aryl-7-trifluoromethylindazole, 19::3-(4-chlorophenyl)-2-[(2-chlorophenyl)methyl]-7-(trifluoromethyl)-2H-indazole

SMILES FC(F)(F)c1cccc2c(-c3ccc(Cl)cc3)n(Cc3ccccc3Cl)nc12

InChI Key InChIKey=DTDVBYRJYQLMSF-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 26073   

TargetOxysterols receptor LXR-alpha [197-447](Human)
Wyeth Research

LigandPNGBDBM26073(2-benzyl-3-aryl-7-trifluoromethylindazole, 19 | 3-...)
Affinity DataIC50:  379nM EC50:  1.52E+4nMAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandPNGBDBM26073(2-benzyl-3-aryl-7-trifluoromethylindazole, 19 | 3-...)
Affinity DataIC50:  40nM EC50:  1.02E+4nMpH: 7.4 T: 4°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed