BDBM2608 3-(5-amino-1-methyl-1H-indol-3-yl)-4-(1-methyl-1H-indol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione::Bisindolylmaleimide deriv. 30::ROCHE screening, 43

SMILES Cn1cc(C2=C(C(=O)NC2=O)c2cn(C)c3ccc(N)cc23)c2ccccc12

InChI Key InChIKey=LSAVPOITAZCHEO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 2608   

TargetSerine/threonine-protein kinase TBK1(Human)
Technical University of Dortmund

LigandPNGBDBM2608(3-(5-amino-1-methyl-1H-indol-3-yl)-4-(1-methyl-1H-...)
Affinity DataIC50:  3.37E+3nMAssay Description:IC50 determinations for TBK1 were performed with the KinEASE-STK assay from Cisbio according to the manufacturer's instructions. A biotinylated s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM2608(3-(5-amino-1-methyl-1H-indol-3-yl)-4-(1-methyl-1H-...)
Affinity DataIC50:  490nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed