BDBM261657 N-(4-(3-((3,5-bis(trifluoromethyl)phenyl)ethynyl)phenyl)thiazol-2-yl)-5-(4-(4-methylpiperazine-1-carbonyl)phenyl)furan-2-carboxamide::US9708279, 34

SMILES CN1CCN(CC1)C(=O)c1ccc(cc1)-c1ccc(o1)C(=O)Nc1nc(cs1)-c1cccc(c1)C#Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=JUYMOSAMZBUMKZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 261657   

TargetALK tyrosine kinase receptor [L1196M](Human)
UniversitÁ

US Patent
LigandChemical structure of BindingDB Monomer ID 261657BDBM261657(N-(4-(3-((3,5-bis(trifluoromethyl)phenyl)ethynyl)p...)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetALK tyrosine kinase receptor(Human)
UniversitÁ

US Patent
LigandChemical structure of BindingDB Monomer ID 261657BDBM261657(N-(4-(3-((3,5-bis(trifluoromethyl)phenyl)ethynyl)p...)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent