BDBM261660 N-(4-(4-((tert-butyldimethylsilyl)ethynyl)phenyl)thiazol-2-yl)-4-((4-methylpiperazin-1-yl)methyl)benzamide::US9708279, 37
SMILES CN1CCN(Cc2ccc(cc2)C(=O)Nc2nc(cs2)-c2ccc(cc2)C#C[Si](C)(C)C(C)(C)C)CC1
InChI Key InChIKey=TUGBZRBAAFTUGF-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 261660
Affinity DataIC50: 2.10E+3nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
Affinity DataIC50: 4.60E+3nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair