BDBM261663 N-(4-(3-((tert-butyldimethylsilyl)ethynyl)phenyl)thiazol-2-yl)-4-(morpholinomethyl)benzamide::US9708279, 40

SMILES CC(C)(C)[Si](C)(C)C#Cc1cccc(c1)-c1csc(NC(=O)c2ccc(CN3CCOCC3)cc2)n1

InChI Key InChIKey=QAXWBDUABCOHMB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 261663   

TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
UniversitÁ

US Patent
LigandPNGBDBM261663(N-(4-(3-((tert-butyldimethylsilyl)ethynyl)phenyl)t...)
Affinity DataIC50:  4.40E+3nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
UniversitÁ

US Patent
LigandPNGBDBM261663(N-(4-(3-((tert-butyldimethylsilyl)ethynyl)phenyl)t...)
Affinity DataIC50:  9.40E+3nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent