BDBM261715 4-((6-Chloropyridin-3-yl)methyl)-1-fluoro-N-((1SR,2SR)-2-hydroxycyclohexyl)-2-naphthamide::US9708302, 1::US9708302, 3

SMILES O[C@H]1CCCC[C@@H]1NC(=O)c1cc(Cc2ccc(Cl)nc2)c2ccccc2c1F

InChI Key InChIKey=ODFVXVSVXQOSMG-PMACEKPBSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 261715   

TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM261715(4-((6-Chloropyridin-3-yl)methyl)-1-fluoro-N-((1SR,...)
Affinity DataEC50:  159nMAssay Description:The assay is designed to select compounds that possess modulator activity at the acetylcholine muscarinic receptor expressed in CHO cells by measurin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M1(RAT)
Hoffmann-La Roche

US Patent
LigandPNGBDBM261715(4-((6-Chloropyridin-3-yl)methyl)-1-fluoro-N-((1SR,...)
Affinity DataEC50:  101nMAssay Description:The assay is designed to select compounds that possess modulator activity at the acetylcholine muscarinic receptor expressed in CHO cells by measurin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M1(RAT)
Hoffmann-La Roche

US Patent
LigandPNGBDBM261715(4-((6-Chloropyridin-3-yl)methyl)-1-fluoro-N-((1SR,...)
Affinity DataEC50:  137nMAssay Description:The assay is designed to select compounds that possess modulator activity at the acetylcholine muscarinic receptor expressed in CHO cells by measurin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM261715(4-((6-Chloropyridin-3-yl)methyl)-1-fluoro-N-((1SR,...)
Affinity DataEC50:  84nMAssay Description:The assay is designed to select compounds that possess modulator activity at the acetylcholine muscarinic receptor expressed in CHO cells by measurin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent