BDBM261735 1-fluoro-N-((3S,4S)-4- hydroxytetrahydro-2H- pyran-3-yl)-4-((6-(1- methyl-1H-pyrazol-4- yl)pyridin-3-yl)- methyl)-2- naphthamide::US9708302, 21

SMILES Cn1cc(cn1)-c1ccc(Cc2cc(C(=O)N[C@H]3COCC[C@@H]3O)c(F)c3ccccc23)cn1

InChI Key InChIKey=LTAVPOIOWAMMGH-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 261735   

TargetMuscarinic acetylcholine receptor M1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM261735(1-fluoro-N-((3S,4S)-4- hydroxytetrahydro-2H- pyran...)
Affinity DataEC50:  33nMAssay Description:The assay is designed to select compounds that possess modulator activity at the acetylcholine muscarinic receptor expressed in CHO cells by measurin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2018
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M1(Rat)
Hoffmann-La Roche

US Patent
LigandPNGBDBM261735(1-fluoro-N-((3S,4S)-4- hydroxytetrahydro-2H- pyran...)
Affinity DataEC50:  48nMAssay Description:The assay is designed to select compounds that possess modulator activity at the acetylcholine muscarinic receptor expressed in CHO cells by measurin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2018
Entry Details
US Patent