BDBM261738 4-((6-Cyclopropylpyridin-3-yl)methyl)-1-fluoro-N-((1S,2S)-2-hydroxycyclohexyl)-2-naphthamide::US9708302, 24

SMILES O[C@H]1CCCC[C@@H]1NC(=O)c1cc(Cc2ccc(nc2)C2CC2)c2ccccc2c1F

InChI Key InChIKey=ZMXFQJRULXTKRX-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 261738   

TargetMuscarinic acetylcholine receptor M1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM261738(4-((6-Cyclopropylpyridin-3-yl)methyl)-1-fluoro-N-(...)
Affinity DataEC50:  230nMAssay Description:The assay is designed to select compounds that possess modulator activity at the acetylcholine muscarinic receptor expressed in CHO cells by measurin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2018
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M1(Rat)
Hoffmann-La Roche

US Patent
LigandPNGBDBM261738(4-((6-Cyclopropylpyridin-3-yl)methyl)-1-fluoro-N-(...)
Affinity DataEC50:  347nMAssay Description:The assay is designed to select compounds that possess modulator activity at the acetylcholine muscarinic receptor expressed in CHO cells by measurin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2018
Entry Details
US Patent