BDBM262119 6-Amino-2-(methylsulfonimidoyl)-9-(2-pyridylmethyl)-7H-purin-8-one::US11242345, Example 19::US9708325, 19

SMILES CS(=N)(=O)c1nc(N)c2[nH]c(=O)n(Cc3ccccn3)c2n1

InChI Key

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 262119   

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM262119(6-Amino-2-(methylsulfonimidoyl)-9-(2-pyridylmethyl...)
Affinity DataEC50:  670nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM262119(6-Amino-2-(methylsulfonimidoyl)-9-(2-pyridylmethyl...)
Affinity DataEC50:  670nMAssay Description:HEK-Blue-hTLR7 cells were incubated at a density of 250,000˜450,000 cells/mL in a volume of 180 μL in a 96-well plate in Dulbecco's Mod...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent