BDBM26269 3,5-dichloro-2-hydroxybenzoic acid::3,5-dichlorosalicylic acid::CHEMBL449129
SMILES OC(=O)c1cc(Cl)cc(Cl)c1O
InChI Key InChIKey=CNJGWCQEGROXEE-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 26269
Affinity DataKi: 5.90nM ΔG°: -11.2kcal/molepH: 7.4 T: 2°CAssay Description:The activity was assayed by measuring the rate of change in NADPH fluorescence (at 455 nm with an excitation wavelength of 340 nm) at 298 K. When the...More data for this Ligand-Target Pair
Affinity DataKi: 5.90nMAssay Description:Inhibition of human wild type AKR1C1 dehydrogenase activity by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 6.60nMAssay Description:Competitive inhibition of human recombinant AKR1C1 Phe311Ala mutant by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Competitive inhibition of human recombinant AKR1C1 Phe311Leu mutant by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 58nM ΔG°: -9.87kcal/molepH: 7.4 T: 2°CAssay Description:The activity was assayed by measuring the rate of change in NADPH fluorescence (at 455 nm with an excitation wavelength of 340 nm) at 298 K. When the...More data for this Ligand-Target Pair
Affinity DataKi: 70nM ΔG°: -9.75kcal/molepH: 7.4 T: 2°CAssay Description:The activity was assayed by measuring the rate of change in NADPH fluorescence (at 455 nm with an excitation wavelength of 340 nm) at 298 K. When the...More data for this Ligand-Target Pair
Affinity DataKi: 70nMAssay Description:Inhibition of human AKR1C2 dehydrogenase activity by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 85nM ΔG°: -9.64kcal/molepH: 7.4 T: 2°CAssay Description:The activity was assayed by measuring the rate of change in NADPH fluorescence (at 455 nm with an excitation wavelength of 340 nm) at 298 K. When the...More data for this Ligand-Target Pair
Affinity DataKi: 270nM ΔG°: -8.95kcal/molepH: 7.4 T: 2°CAssay Description:The activity was assayed by measuring the rate of change in NADPH fluorescence (at 455 nm with an excitation wavelength of 340 nm) at 298 K. When the...More data for this Ligand-Target Pair
Affinity DataKi: 2.80E+3nM ΔG°: -7.57kcal/molepH: 7.4 T: 2°CAssay Description:The activity was assayed by measuring the rate of change in NADPH fluorescence (at 455 nm with an excitation wavelength of 340 nm) at 298 K. When the...More data for this Ligand-Target Pair
Affinity DataKi: 2.40E+4nM ΔG°: -6.30kcal/molepH: 7.4 T: 2°CAssay Description:The activity was assayed by measuring the rate of change in NADPH fluorescence (at 455 nm with an excitation wavelength of 340 nm) at 298 K. When the...More data for this Ligand-Target Pair
Affinity DataKi: 9.40E+4nM ΔG°: -5.49kcal/molepH: 7.4 T: 2°CAssay Description:The activity was assayed by measuring the rate of change in NADPH fluorescence (at 455 nm with an excitation wavelength of 340 nm) at 298 K. When the...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member A1(Sus scrofa)
Monash University (Parkville Campus)
Curated by ChEMBL
Monash University (Parkville Campus)
Curated by ChEMBL
Affinity DataIC50: 1.13E+4nMAssay Description:Inhibition of pig ALR1More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of 20-alpha HSD (unknown origin)More data for this Ligand-Target Pair