BDBM262808 3-[4-(2-hydroxyethyl)piperidin-1-yl]- 2-(1H-tetrazol-5-yl)-6- (trifluoromethyl)benzenesulfonamide::US9708336, 661

SMILES NS(=O)(=O)c1c(ccc(N2CCC(CCO)CC2)c1-c1nnn[nH]1)C(F)(F)F

InChI Key InChIKey=DGYNHLCPOVDSJN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 262808   

TargetMetallo-beta-lactamase type 2(Serratia marcescens)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM262808(3-[4-(2-hydroxyethyl)piperidin-1-yl]- 2-(1H-tetraz...)
Affinity DataIC50:  0.965nMpH: 7.0Assay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVIM-1 metallo-beta-lactamase(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM262808(3-[4-(2-hydroxyethyl)piperidin-1-yl]- 2-(1H-tetraz...)
Affinity DataIC50:  0.220nMpH: 7.0Assay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM262808(3-[4-(2-hydroxyethyl)piperidin-1-yl]- 2-(1H-tetraz...)
Affinity DataIC50:  1.01nMpH: 7.0Assay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent