BDBM263 (S)-5-({5-[1-Carboxymethyl-2-oxo-3-(pyridin-3-ylmeth-ylsulfanyl)propylcarbamoyl]thiophen-2-ylmethyl}-sulfamoyl)-2-hydroxy-benzoic Acid::5-{[(5-{[(2S)-1-carboxy-3-oxo-4-[(pyridin-3-ylmethyl)sulfanyl]butan-2-yl]carbamoyl}thiophen-2-yl)methyl]sulfamoyl}-2-hydroxybenzoic acid::Inhibitor 71::Thiophene Scaffold 71

SMILES OC(=O)C[C@H](NC(=O)c1ccc(CNS(=O)(=O)c2ccc(O)c(c2)C(O)=O)s1)C(=O)CSCc1cccnc1

InChI Key InChIKey=QHKQIPCBIONNNA-SFHVURJKSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 263   

TargetCaspase-3(Human)
Sunesis Pharmaceuticals

LigandPNGBDBM263((S)-5-({5-[1-Carboxymethyl-2-oxo-3-(pyridin-3-ylme...)
Affinity DataKi:  20nM ΔG°:  -10.5kcal/molepH: 7.4 T: 25°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed