BDBM26319 2-[5-(2-{thieno[3,2-d]pyrimidin-4-ylamino}ethyl)-1,3-thiazol-2-yl]-N-[3-(trifluoromethyl)phenyl]acetamide::thieno[3,2-d]pyrimidine analogue, 14

SMILES FC(F)(F)c1cccc(NC(=O)Cc2ncc(CCNc3ncnc4ccsc34)s2)c1

InChI Key InChIKey=USSPDYYDWFNICI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 26319   

TargetAurora kinase B(Human)
Sunesis Pharmaceuticals

LigandPNGBDBM26319(2-[5-(2-{thieno[3,2-d]pyrimidin-4-ylamino}ethyl)-1...)
Affinity DataIC50:  442nMAssay Description:Compounds were diluted into assay buffer containing Aurora kinase and FAM-PKAtide. The kinase reaction was initiated by adding ATP in assay buffer. T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetAurora kinase A(Mouse)
Sunesis Pharmaceuticals

LigandPNGBDBM26319(2-[5-(2-{thieno[3,2-d]pyrimidin-4-ylamino}ethyl)-1...)
Affinity DataIC50:  4.90E+3nMpH: 7.2 T: 21°CAssay Description:Compounds were diluted into assay buffer containing Aurora kinase and FAM-PKAtide. The kinase reaction was initiated by adding ATP in assay buffer. T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed