BDBM263215 1-[4-(4-methyl-pyrazol-1-ylmethyl)-benzyl]-1h-imidazole-4-carboxylic acid (1-amino-isoquinolin-6-ylmethyl)-amide::US9533987, example 10::US9533987, example 32
SMILES Cc1cnn(Cc2ccc(Cn3cnc(c3)C(=O)NCc3ccc4c(N)nccc4c3)cc2)c1
InChI Key InChIKey=MCLBVPPTLFLLSH-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 263215
Affinity DataIC50: 2.40nMAssay Description:Plasma kallikrein inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Plasma kallikrein inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Human serine protease enzymes plasmin, thrombin, trypsin, Factor Xa and Factor XIIa were assayed for enzymatic activity using an appropriate fluoroge...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Human serine protease enzymes plasmin, thrombin, trypsin, Factor Xa and Factor XIIa were assayed for enzymatic activity using an appropriate fluoroge...More data for this Ligand-Target Pair