BDBM26322 1-(3-methylphenyl)-3-[5-(2-{thieno[3,2-d]pyrimidin-4-ylamino}ethyl)-1,3-thiazol-2-yl]urea::thieno[3,2-d]pyrimidine analogue, 17

SMILES Cc1cccc(NC(=O)Nc2ncc(CCNc3ncnc4ccsc34)s2)c1

InChI Key InChIKey=NVJBRKUSNQZNKX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 26322   

TargetAurora kinase B(Human)
Sunesis Pharmaceuticals

LigandPNGBDBM26322(1-(3-methylphenyl)-3-[5-(2-{thieno[3,2-d]pyrimidin...)
Affinity DataIC50:  54nMAssay Description:Compounds were diluted into assay buffer containing Aurora kinase and FAM-PKAtide. The kinase reaction was initiated by adding ATP in assay buffer. T...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAurora kinase A(Mouse)
Sunesis Pharmaceuticals

LigandPNGBDBM26322(1-(3-methylphenyl)-3-[5-(2-{thieno[3,2-d]pyrimidin...)
Affinity DataIC50:  9nMpH: 7.2 T: 21°CAssay Description:Compounds were diluted into assay buffer containing Aurora kinase and FAM-PKAtide. The kinase reaction was initiated by adding ATP in assay buffer. T...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed