BDBM263408 (R)-5-cyclopropyl-N-(cyclopropylsulfonyl)-4-((1-(3,5-dichlorophenyl)piperidin-3-yl)oxy)-2-fluorobenzamide::US9546164, 42::US9546164, 43::US9546164, 44

SMILES NC(=O)c1cc(C2CC2)c(O[C@@H]2CCCN(C2)c2cc(Cl)cc(Cl)c2)cc1F

InChI Key InChIKey=JSDMLFVZNXJIGL-MRXNPFEDSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 263408   

TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM263408((R)-5-cyclopropyl-N-(cyclopropylsulfonyl)-4-((1-(3...)
Affinity DataIC50:  2.10nMpH: 7.4 T: 2°CAssay Description:Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) having a methyl group was tritiated. Three tritiums wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM263408((R)-5-cyclopropyl-N-(cyclopropylsulfonyl)-4-((1-(3...)
Affinity DataIC50:  3.60nMpH: 7.4 T: 2°CAssay Description:Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) having a methyl group was tritiated. Three tritiums wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM263408((R)-5-cyclopropyl-N-(cyclopropylsulfonyl)-4-((1-(3...)
Affinity DataIC50:  4.90nMpH: 7.4 T: 2°CAssay Description:Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) having a methyl group was tritiated. Three tritiums wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent