BDBM263612 2-(tert-butyl)-4-chloro-5-((4-(4-fluorobut-1-yn-1-yl)benzyl)oxy)pyridazin-3(2H)-one::US9713651, 43

SMILES CC(C)(C)n1ncc(OCc2ccc(cc2)C#CCCF)c(Cl)c1=O

InChI Key InChIKey=GXUSXZGOVILUFY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 263612   

TargetNADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial(Bovine)
Lantheus Medical Imaging

US Patent
LigandPNGBDBM263612(2-(tert-butyl)-4-chloro-5-((4-(4-fluorobut-1-yn-1-...)
Affinity DataIC50: <100nMpH: 7.4Assay Description:The procedure for determining catalytic activity of submitochondrial particles was adapted from Satoh et al. (e.g., see Satoh T, Miyoshi H, Sakamoto ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent