BDBM263646 2-(tert-butyl)-4-chloro-5-((4-((2-fluoropyridin-3-yl)oxy)benzyl)oxy)pyridazin-3(2H)-one::US9713651, 56D

SMILES CC(C)(C)n1ncc(OCc2ccc(Oc3cccnc3F)cc2)c(Cl)c1=O

InChI Key InChIKey=MDPOFZQRXBKIOK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 263646   

TargetNADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial(Bovine)
Lantheus Medical Imaging

US Patent
LigandPNGBDBM263646(2-(tert-butyl)-4-chloro-5-((4-((2-fluoropyridin-3-...)
Affinity DataIC50: 100nMpH: 7.4Assay Description:The procedure for determining catalytic activity of submitochondrial particles was adapted from Satoh et al. (e.g., see Satoh T, Miyoshi H, Sakamoto ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent