BDBM263692 US9714221, Example 29

SMILES COc1ccc(c(F)c1)C1=C(c2ccc(O[C@H]3CCN(CCCF)C3)cc2)c2ccc(O)cc2CCC1

InChI Key InChIKey=OJORZZZISIXVNW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 263692   Sort by

TargetEstrogen receptor(Human)
Sanofi

US Patent
LigandPNGBDBM263692(US9714221, Example 29)
Affinity DataIC50: 2nMpH: 7.4 T: 2°CAssay Description:It is a competition assay, where binding of a test compound to a complex comprised of (i) His6-ERα298-554 protein representing ERα ligand-b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetEstrogen receptor [D538G](Human)
Sanofi

US Patent
LigandPNGBDBM263692(US9714221, Example 29)
Affinity DataIC50: 4nMpH: 7.4 T: 2°CAssay Description:It is a competition assay, where binding of a test compound to a complex comprised of (i) His6-ERα298-554 protein representing ERα ligand-b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetEstrogen receptor [Y537S](Human)
Sanofi

US Patent
LigandPNGBDBM263692(US9714221, Example 29)
Affinity DataIC50: 2nMpH: 7.4 T: 2°CAssay Description:It is a competition assay, where binding of a test compound to a complex comprised of (i) His6-ERα298-554 protein representing ERα ligand-b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent