BDBM263760 5-[4-[(3S)- 1-(3- fluoropropyl)- pyrrolidin-3- yl]oxy- phenyl]-6-[4- (trifluoro- methyl- sulfanyl)- phenyl]- 8,9- dihydro- 7H- benzo[7]- annulen-2-ol::US9714221, Example 94
SMILES Oc1ccc2c(CCCC(c3ccc(SC(F)(F)F)cc3)=C2c2ccc(O[C@H]3CCN(CCCF)C3)cc2)c1
InChI Key InChIKey=KSHPIANNCSKMIT-SANMLTNESA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 263760
Affinity DataIC50: 25nMpH: 7.4 T: 2°CAssay Description:It is a competition assay, where binding of a test compound to a complex comprised of (i) His6-ERα298-554 protein representing ERα ligand-b...More data for this Ligand-Target Pair
Affinity DataEC50: 2nMAssay Description:Induction of ERalpha degradation in human MCF7 cells incubated for 4 hrs by Alexafluor-488 conjugate anti-rabbit antibody/Syto-64 staining based immu...More data for this Ligand-Target Pair
Affinity DataIC50: 322nMpH: 7.4 T: 2°CAssay Description:It is a competition assay, where binding of a test compound to a complex comprised of (i) His6-ERα298-554 protein representing ERα ligand-b...More data for this Ligand-Target Pair
Affinity DataIC50: 485nMpH: 7.4 T: 2°CAssay Description:It is a competition assay, where binding of a test compound to a complex comprised of (i) His6-ERα298-554 protein representing ERα ligand-b...More data for this Ligand-Target Pair