BDBM263801 6-(2,2- difluoro- 1,3- benzo- dioxol-5-yl)-5- [4-[(3S)-1- (3- fluoropropyl)- pyrrolidin-3- yl]oxy- phenyl]- 8,9- dihydro- 7H- benzo[7]- annulen-2-ol::US9714221, Example 134

SMILES Oc1ccc2c(CCCC(c3ccc4OC(F)(F)Oc4c3)=C2c2ccc(O[C@H]3CCN(CCCF)C3)cc2)c1

InChI Key InChIKey=XLGXLDLBOICQPN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 263801   Sort by

TargetEstrogen receptor(Human)
Sanofi

US Patent
LigandPNGBDBM263801(6-(2,2- difluoro- 1,3- benzo- dioxol-5-yl)-5- [4-[...)
Affinity DataIC50: 2nMpH: 7.4 T: 2°CAssay Description:It is a competition assay, where binding of a test compound to a complex comprised of (i) His6-ERα298-554 protein representing ERα ligand-b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetEstrogen receptor [D538G](Human)
Sanofi

US Patent
LigandPNGBDBM263801(6-(2,2- difluoro- 1,3- benzo- dioxol-5-yl)-5- [4-[...)
Affinity DataIC50: 28nMpH: 7.4 T: 2°CAssay Description:It is a competition assay, where binding of a test compound to a complex comprised of (i) His6-ERα298-554 protein representing ERα ligand-b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetEstrogen receptor [Y537S](Human)
Sanofi

US Patent
LigandPNGBDBM263801(6-(2,2- difluoro- 1,3- benzo- dioxol-5-yl)-5- [4-[...)
Affinity DataIC50: 28nMpH: 7.4 T: 2°CAssay Description:It is a competition assay, where binding of a test compound to a complex comprised of (i) His6-ERα298-554 protein representing ERα ligand-b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent