BDBM263923 US9714221, Example 219N/A*: Not available. Prodrug of example 75

SMILES CC(F)(F)c1ccc(C2=C(c3ccc(O[C@H]4CCN(CCCF)C4)cc3)c3ccc(C(=O)O)cc3CCC2)cc1

InChI Key InChIKey=QANHCDDKESZFOG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 263923   

TargetType-2 angiotensin II receptor(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 263923BDBM263923(US9714221, Example 219N/A*: Not available. Prodrug...)
Affinity DataIC50: 431nMAssay Description:120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs. The binding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent