BDBM265 (S)-5-({5-[1-Carboxymethyl-5-(2-chloro-phenyl)-2-oxo-pentylcarbamoyl]thiophen-2-ylmethyl}sulfamoyl)-2-hydroxy-benzoic Acid::5-{[(5-{[(2S)-1-carboxy-3-oxo-6-phenylhexan-2-yl]carbamoyl}thiophen-2-yl)methyl]sulfamoyl}-2-hydroxybenzoic acid::Inhibitor 73::Thiophene Scaffold 73

SMILES OC(=O)C[C@H](NC(=O)c1ccc(CNS(=O)(=O)c2ccc(O)c(c2)C(O)=O)s1)C(=O)CCCc1ccccc1

InChI Key InChIKey=IAZHUZNOJTUKSY-FQEVSTJZSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 265   

TargetCaspase-3(Human)
Sunesis Pharmaceuticals

LigandPNGBDBM265((S)-5-({5-[1-Carboxymethyl-5-(2-chloro-phenyl)-2-o...)
Affinity DataKi:  240nM ΔG°:  -9.02kcal/molepH: 7.4 T: 25°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed