BDBM26525 (1S,2R)-1-N-hydroxy-2-({4-[(2-phenylquinolin-4-yl)methoxy]phenyl}methyl)cyclopropane-1,2-dicarboxamide::hydroxamate-cyclopropyl compound, 2

SMILES NC(=O)[C@@]1(Cc2ccc(OCc3cc(nc4ccccc34)-c3ccccc3)cc2)C[C@@H]1C(=O)NO

InChI Key InChIKey=BKHGWMSYWJIRLD-LXFBAYGMSA-N

Data  2 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 26525   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM26525((1S,2R)-1-N-hydroxy-2-({4-[(2-phenylquinolin-4-yl)...)
Affinity DataKi:  0.180nMAssay Description:Inhibition of human recombinant TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB
PDB3D3D Structure (crystal)

LigandPNGBDBM26525((1S,2R)-1-N-hydroxy-2-({4-[(2-phenylquinolin-4-yl)...)
Affinity DataKi:  0.180nM ΔG°:  -13.2kcal/molepH: 7.3 T: 22°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB
PDB3D3D Structure (crystal)