BDBM26546 (3R)-1-[(4-{[4-(piperidin-1-yl)but-2-yn-1-yl]oxy}benzene)sulfonyl]pyrrolidine-3-thiol::thiol-arylsulfonamide, 12a
SMILES S[C@@H]1CCN(C1)S(=O)(=O)c1ccc(OCC#CCN2CCCCC2)cc1
InChI Key InChIKey=WQXRLQZSXRETEV-GOSISDBHSA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 26546
TargetDisintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q](Human)
Vertex Pharmaceuticals
Vertex Pharmaceuticals
Affinity DataKi: 530nM ΔG°: -8.47kcal/molepH: 7.5 T: 22°CAssay Description:The compounds were tested for TACE inhibition using fluorescence resonance energy transfer (FRET) assay. TACE catalyzed cleavage of the substrate pep...More data for this Ligand-Target Pair