BDBM26683 2-{3-amino-4-phenyl-1H-pyrazolo[3,4-b]pyridin-6-yl}-4-bromophenol::pyrazolopyridine, 11

SMILES Nc1n[nH]c2nc(cc(-c3ccccc3)c12)-c1cc(Br)ccc1O

InChI Key InChIKey=CZDDKQGCFAHRBQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 26683   

TargetSerine/threonine-protein kinase pim-1(Human)
Joint Research Institution of Altitude Health and Institute of Respiratory Health and National Clinical Research Center for Geriatrics

Curated by ChEMBL
LigandPNGBDBM26683(2-{3-amino-4-phenyl-1H-pyrazolo[3,4-b]pyridin-6-yl...)
Affinity DataIC50: 1.77E+3nMAssay Description:Inhibition of human PIM1 by discoverX kinome scan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Joint Research Institution of Altitude Health and Institute of Respiratory Health and National Clinical Research Center for Geriatrics

Curated by ChEMBL
LigandPNGBDBM26683(2-{3-amino-4-phenyl-1H-pyrazolo[3,4-b]pyridin-6-yl...)
Affinity DataIC50: 1.77E+3nMpH: 7.5 T: 2°CAssay Description:PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2009
Entry Details Article
PubMed