BDBM267394 3-chloro-5-((4-(1,1-difluoroethyl)-1-((5-(4-fluorophenyl)-6-oxo-1,6-dihydropyridazin-3-yl)methyl)-6-oxo-1,6-dihydropyrimidin-5-yl)oxy)benzonitrile::US10189831, Example 170::US9718819, 170

SMILES CC(F)(F)c1ncn(Cc2cc(-c3ccc(F)cc3)c(=O)[nH]n2)c(=O)c1Oc1cc(Cl)cc(c1)C#N

InChI Key InChIKey=CYUNVKSWQRVDRM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 267394   

TargetGag-Pol polyprotein(HIV-1)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267394(3-chloro-5-((4-(1,1-difluoroethyl)-1-((5-(4-fluoro...)
Affinity DataIC50: 5nMpH: 7.8 T: 2°CAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details
US Patent

TargetGag-Pol polyprotein(HIV-1)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267394(3-chloro-5-((4-(1,1-difluoroethyl)-1-((5-(4-fluoro...)
Affinity DataIC50: 5nMAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent